Characterization of integrin ?6 and thrombospondin-1 double-null mice
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چکیده
منابع مشابه
Flu virus susceptibility of ago 1 / 3 double null mice Enhanced Susceptibility to Influenza A Virus of Ago 1 / 3 1 Double Null Mice
22 RNAi is a critical component of many cellular anti-viral responses in plants, 23 invertebrates, and mammals. However, its in vivo role in host protection from the 24 negative sense RNA virus Influenza Type A is unclear. Here we have examined the role 25 of RNAi in host defense to flu by analyzing Argonaute 1 and 3 double knock out mice, 26 deficient in components of the RNA induced silencing...
متن کاملFlu virus susceptibility of ago 1 / 3 double null mice Enhanced Susceptibility to Influenza A Virus of Ago 1 / 3 1 Double Null Mice 2
22 RNAi is a critical component of many cellular anti-viral responses in plants, 23 invertebrates, and mammals. However, its in vivo role in host protection from the 24 negative sense RNA virus Influenza Type A is unclear. Here we have examined the role 25 of RNAi in host defense to flu by analyzing Argonaute 1 and 3 double knock out mice, 26 deficient in components of the RNA induced silencing...
متن کامل"Time sweet time": circadian characterization of galectin-1 null mice
BACKGROUND Recent evidence suggests a two-way interaction between the immune and circadian systems. Circadian control of immune factors, as well as the effect of immunological variables on circadian rhythms, might be key elements in both physiological and pathological responses to the environment. Among these relevant factors, galectin-1 is a member of a family of evolutionarily-conserved glyca...
متن کاملThrombospondin-1 null mice are resistant to hypoxia-induced pulmonary hypertension
BACKGROUND AND OBJECTIVE Chronic hypoxia induces pulmonary hypertension in mice. Smooth muscle cell hyperplasia and medial thickening characterize the vasculature of these animals. Thrombospondin-1 null (TSP-1(-/-)) mice spontaneously develop pulmonary smooth muscle cell hyperplasia and medial thickening. In addition, TSP-1 produced by the pulmonary endothelium inhibits pulmonary artery smooth ...
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ماکروسیکلهای شیف باز از اهمیت زیادی در شیمی آلی و دارویی برخوردار می باشند. این ماکروسیکلها با دارابودن گروه های مناسب در مکانهای مناسب می توانند فلزاتی مثل مس، نیکل و ... را در حفره های خود به دام انداخته، کمپلکسهای پایدار تولید نمایند. در این پایان نامه ابتدا یک دی آلدئید آروماتیک از گلیسیرین تهیه می شود و در مرحله بعدی واکنش با دی آمینهای آروماتیک و یا آلیفاتیک در رقتهای بسیار زیاد منجر به ت...
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ژورنال
عنوان ژورنال: Journal of Cellular and Molecular Medicine
سال: 2005
ISSN: 1582-1838,1582-4934
DOI: 10.1111/j.1582-4934.2005.tb00367.x